"Do not sacrifice the safety, the security and the stability of 300 million Americans for the legacy of one man," implored Rep. Mike Kelly (R-Pa.) as he stood next to a poster of the Twin Towers burning on Sept. 11, 2001.

In addition to opposing the resolution, The House passed legislation 247-186 that would prevent Obama from lifting sanctions against Iran. That measure would expire when Obama's successor takes office in January 2017.

The Hill reported on Friday that on September 10, "Senate Democrats blocked a resolution disapproving the Iran deal, leaving Republicans without a clear path forward for stopping the deal." Senate Republicans continue to say they will hold more votes on Iran next week.

"The Democrats in the House who opposed the Iran deal were a mix of lawmakers with different backgrounds and political situations. Some of them represent Jewish constituencies, face tough reelection races next year or identify as centrists," according to The Hill.

The 25 Democrats who voted against approving the Iran deal were Reps. Brad Ashford (Neb.), Brendan Boyle (Pa.), Tony Cardenas (Calif.), Ted Deutch (Fla.), Eliot Engel (N.Y.), Lois Frankel (Fla.), Gwen Graham (Fla.), Gene Green (Texas), Alcee Hastings (Fla.), Steve Israel (N.Y.), Ted Lieu (Calif.), Dan Lipinski (Ill.), Nita Lowey (N.Y.), Carolyn Maloney (N.Y.), Grace Meng (N.Y.), Grace Napolitano (Calif.), Donald Norcross (N.J.), Collin Peterson (Minn.), Kathleen Rice (N.Y.), David Scott (Ga.), Brad Sherman (Calif.), Kyrsten Sinema (Ariz.), Albio Sires (N.J.), Juan Vargas (Calif.) and Filemon Vela (Texas).

Despite the 25 defections, enough Democrats voted to support the deal and deprived the GOP of a veto-proof majority.