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Friday, 30 September 2016 09:47

Zika and the GM Mosquitoes Part III Featured

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Well here we go again, the
more research I do the scarier this
Zika Virus/ GM mosquito correlation
becomes.
All the news seems to be
focused around the information
that the Zika virus in pregnant
women can be devastating, Why?
because we've had more than 4,200
cases of pregnancies in Brazil
where developing fetus
is missing part of the
brain or has a small head
which is described as microcephaly.
But as I have previously
reported Zika has
been around for a while.
The virus named for the
forest in Uganda where it
was first reported in the
Rhesus monkey in the
late forties.
The first major
outbreak in humans was
in Micronesia on the island
of Yap in 2007 where 3500 of
the five thousand inhabitants were
infected, there were no birth were
reported.
A much larger outbreak
was reported in French Polynesia
in 2013 and 2014 where 30,000
people were affected, again no
fetal abnormalities were identified,
when they saw it was happening in
Brazil they went back and found
17 cases of microcephaly out of
30,000 infected people.
So when we look at that, in
truth, the first explosion of microcephaly
cases that have been tried
to be linked with Zika happened in
Brazil.
And ......Brazil happens to
be where they started testing these
genetically modified mosquitoes
from the company Oxitec.
So originally, it appeared
that these genetically modified
mosquitoes actually spreading the
Zika virus, but I don't think that is
actually the problem, the problem
is the genetically modified mosquitoes
inserting the genetic coding
which is meant to disrupt the reproduction
of the female mosquitoes
and it is disrupting the reproduction
of human fetuses. That is
what appears to be happening.
Now remember that no
connection to microcephaly and
the Zika virus has ever been even
considered up until this outbreak in
Brazil, and even now the medical
community is being very cautious
in stating that there's no evidence
that the Zika virus is causing this
microcephaly in newborns. A report
from New England Journal of
Medicine states "no flavivirus has
ever been shown differently to
cause birth defects in humans and
no reports of adverse pregnancy or
birth outcomes were noted during
previous outbreaks of Zika virus
disease in the Pacific Islands"
Again, the first birth defects
were reported right where these
mosquitoes were released in Brazil.
So let's look at how these
mosquitoes work, the male mosquito
is engineering by Oxitec, to
have what they call a "self-limiting"
gene, by inserting the gene
into the target organism it prevents
the insect from surviving into
adulthood . The pest control gene
produces a protein called tTav
(tetracycline repressive activator
variant) whereby the gene ties up
the processes of the other genes so
they can't grow so basically, it kills
the offspring of the female mosquitoes.
So I wondered how do they
breed these male mosquitoes if
they have a gene that makes them
die, well on the Oxitec's website it
says they have an antidote to it;
Tetracycline! Which they call 'tetO'
The tetO antidote is given
to the insects in raring facilities
that binds to the tTav protein and
disables it and acts like a switch to
turn off the tTav gene, preventing
the protein from working. "So in
the presence of the antidote, the
Oxitec insects are able to survive
and reproduce in the rearing facility."
The website goes on to state
that "when the males are released
into the wild their offspring's can't
access the antibiotic in the quantities
needed to survive so they die
before reaching adulthood"
So without the Tetracycline
antidote, "the tTav protein is produced
which simultaneously binds
(at the cellular level) to transcriptional
machinery, (writing code to
keep you alive) making the transcriptionist
scenery unavailable for
other essential gene expression.
The inhibition of the essential gene
expression leads to cell death and
the death of the insect before it
reaches adulthood." ( but, remember
in previous articles, I talked
about how Tetracycline could be
readily available due to it being
given to agricultural food producing
animals and also used as a pesticide
for the citrus groves)
The website goes on to say
that "it's a gene variant that has
been optimized only to work an insect
cells". Just makes you wonder
if they tested on pregnant women
before they started releasing these
mosquitoes Into the Wild?
So let's step back a bit, we
had an explosion of cases of birth
defects right around a place where
male mosquitoes were released
into the wild that were engineered
to give female mosquitoes birth defects.
FROM CNN.com: Sanjay Gupta
writes "Brazil is getting a lot
of attention because the
country has seen a significant
increase in microcephaly.
Previously, there may have
been only 140 cases the
whole year. In Brazil, there
were 4,200 cases in just a
few months, and 51 children
have died. " but when Sanjay
is asked "How serious is the
Zika virus?" he answers:
"For those who aren't
pregnant, most will either
have no symptoms or mild
ones, and it's not serious at
all. Eighty percent of those affected
never know they have the
disease. (that's 4 out of 5) In fact,
what typically happens is that once
you get it, you become immune.
You are essentially now
vaccinated against the virus, because
your body has built up antibodies
and the next time will fight
it."
SO..... when you look at all
the facts it seems the correlation is
pretty strong.
Now the FDA has approved
the release of GM mosquitoes to
fight Zika in Florida, just last
month! And with about 43% of all
antibiotics used in food producing
animals being Tetracycline, I don't
see how these "self-limiting" mosquitoes
will be able to avoid running
into the antidote and thus
reproduce at will.
These are interesting times
we are living in folks!
Don’t worry....new subject next
issue....
Alfredo DiPasquale

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